Najate Achamrah, MD, PhD Associate Professor INSERM Unit 1073: Nutrition, inflammation and gut-microbiota-brain axis Anorexia is associated with a dysregulation of the gut-microbiota-brain axis, including central alterations of food intake regulation, neurotransmission, and peripheral alterations of gut barrier, gut microbiota and immune system. Preserving physical activity during refeeding in patients is beneficial for the restoration